A Nonprofit Making a Global Difference in Tyrosinemia

NOTA Cares works across countries to provide education, advocacy, and community support for Tyrosinemia patients. By collaborating with experts and families, the organization improves access to knowledge and care resources. Its mission is to uplift, inform, and empower affected families everywhere.
notacares.org

Connecting the World Through Tyrosinemia Awareness

Through awareness campaigns, educational content, and patient stories, NOTA Cares strengthens global understanding of Tyrosinemia. The organization encourages early diagnosis, provides practical guidance, and connects families across borders.

https://notacares.org/

Managing Tyrosinemia often requires specific medications that help control symptoms and improve quality of life. With the right medical guidance, these treatments can significantly reduce complications and support better health outcomes.
https://notacares.org/

Why the enzyme defect matters (in everyday language)

Think of the tyrosine breakdown pathway as a factory line. If the last machine (FAH) breaks down, intermediate products pile up and start leaking into other systems. One of those leaked products, succinylacetone, is particularly harmful to liver cells and kidney tubules.

https://notacares.org/