Tadalafil works by inhibiting the enzyme PDE5 (phosphodiesterase type 5), which normally breaks down cyclic GMP, a compound that helps relax the blood vessels in the penis. This relaxation leads to increased blood flow during sexual arousal, helping men achieve and maintain a firm erection.The effects of Tadalafil can last up to 36 hours, giving users a long window of time for spontaneous sexual activity, often referred to as the "weekend pill."
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